Benefits of aerobic exercise in myotonic dystrophy type 1

Myotonic dystrophy type 1 (DM1) is a multisystem trinucleotide repeat expansion disorder characterized by the misregulated alternative splicing of critical mRNAs. Previous work in a transgenic mouse model indicated that aerobic exercise effectively improves splicing regulation and function in skelet...

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Bibliographic Details
Main Authors: Samuel J. Mackenzie, Johanna Hamel, Charles A. Thornton
Format: Article
Language:English
Published: American Society for Clinical Investigation 2022-05-01
Series:The Journal of Clinical Investigation
Online Access:https://doi.org/10.1172/JCI160229