Benefits of aerobic exercise in myotonic dystrophy type 1
Myotonic dystrophy type 1 (DM1) is a multisystem trinucleotide repeat expansion disorder characterized by the misregulated alternative splicing of critical mRNAs. Previous work in a transgenic mouse model indicated that aerobic exercise effectively improves splicing regulation and function in skelet...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
American Society for Clinical Investigation
2022-05-01
|
Series: | The Journal of Clinical Investigation |
Online Access: | https://doi.org/10.1172/JCI160229 |