Characterization of Nasco grape pomace-loaded nutriosomes and their neuroprotective effects in the MPTP mouse model of Parkinson’s disease

Characterization of Nasco grape pomace-loaded nutriosomes and their neuroprotective effects in the MPTP mouse model of Parkinson’s disease

Grape pomaces have recently received great attention for their richness in polyphenols, compounds known to exert anti-inflammatory and antioxidant effects. These pomaces, however, have low brain bioavailability when administered orally due to their extensive degradation in the gastrointestinal tract...

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Bibliographic Details
Main Authors: Pathik Parekh, Marcello Serra, Mohamad Allaw, Matteo Perra, Jacopo Marongiu, Giulia Tolle, Annalisa Pinna, Maria Antonietta Casu, Maria Manconi, Pierluigi Caboni, Olivier J. J. Manzoni, Micaela Morelli
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Pharmacology
Subjects:
grape pomace extract
neurodegeneration
antioxidant activity
neuroprotection
nanotechnology
tyrosine hydoxylase
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.935784/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.935784/full

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