Arctiin alleviates the progression of osteoarthritis by regulating the cholesterol metabolic pathway

Arctiin alleviates the progression of osteoarthritis by regulating the cholesterol metabolic pathway

Abstract Osteoarthritis (OA) is a multi-factorial degenerative joint disease with unclear pathogenesis. Conservative treatments, primarily aimed at pain relief, fail to halt disease progression. Metabolic syndrome has recently been implicated in OA pathogenesis, underscoring the need for novel thera...

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Bibliographic Details
Main Authors: Jiale Mai, Jiacong Xiao, Yanhuai Ma, Dawei Gong, Jianliang Li
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Arctiin
Osteoarthritis treatment
Chondrocyte metabolism
Anti-inflammatory agents
Subchondral Bone
Cholesterol homeostasis
Online Access:https://doi.org/10.1038/s41598-024-83993-1

Internet

https://doi.org/10.1038/s41598-024-83993-1

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