Salmonella Effector SpvB Inhibits NF-κB Activity via KEAP1-Mediated Downregulation of IKKβ

Salmonella Effector SpvB Inhibits NF-κB Activity via KEAP1-Mediated Downregulation of IKKβ

Bacterial pathogens have a broad arsenal of genes that are tightly regulated and coordinated to facilitate adaptation to alter host inflammatory response and prolong intracellular bacterial survival. Salmonella enterica serovar Typhimurium utilizes a type III secretion system (T3SS) to deliver effec...

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Bibliographic Details
Main Authors: Sidi Yang, Qifeng Deng, Lanqing Sun, Yuan Zhu, Kedi Dong, Shuyan Wu, Rui Huang, Yuanyuan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Salmonella
SpvB
NF-κB
IKKβ
KEAP1
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.641412/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2021.641412/full

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