Effect of Solvents, Stabilizers and the Concentration of Stabilizers on the Physical Properties of Poly(<span style="font-variant: small-caps">d</span>,<span style="font-variant: small-caps">l</span>-lactide-<i>co</i>-glycolide) Nanoparticles: Encapsulation, In Vitro Release of Indomethacin and Cytotoxicity against HepG2-Cell

Effect of Solvents, Stabilizers and the Concentration of Stabilizers on the Physical Properties of Poly(<span style="font-variant: small-caps">d</span>,<span style="font-variant: small-caps">l</span>-lactide-<i>co</i>-glycolide) Nanoparticles: Encapsulation, In Vitro Release of Indomethacin and Cytotoxicity against HepG2-Cell

A biocompatible, biodegradable and FDA-approved polymer [Poly lactic-<i>co</i>-glycolic acid (PLGA)] was used to prepare the nanoparticles (NPs) to observe the effect of solvents, stabilizers and their concentrations on the physical properties of the PLGA-NPs, following the encapsulation...

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Bibliographic Details
Main Authors: Musaed Alkholief, Mohd Abul Kalam, Md Khalid Anwer, Aws Alshamsan
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Pharmaceutics
Subjects:
PLGA
Indomethacin
nanoparticles
solvents
stabilizers
morphology
Online Access:https://www.mdpi.com/1999-4923/14/4/870

Internet

https://www.mdpi.com/1999-4923/14/4/870

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