Prediction of bleeding risk in patients taking vitamin K antagonists using thrombin generation testing.

Until recently, vitamin K antagonists (VKAs) were the mainstay of oral anticoagulant treatment with bleeding as the most prevalent adverse effect. One to four percent of patients experience major bleeding episodes, while clinically relevant bleeding occurs in up to 20%. At this moment no laboratory...

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Bibliographic Details
Main Authors: Saartje Bloemen, Suzanne Zwaveling, Hugo Ten Cate, Arina Ten Cate-Hoek, Bas de Laat
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5417600?pdf=render