Prediction of bleeding risk in patients taking vitamin K antagonists using thrombin generation testing.
Until recently, vitamin K antagonists (VKAs) were the mainstay of oral anticoagulant treatment with bleeding as the most prevalent adverse effect. One to four percent of patients experience major bleeding episodes, while clinically relevant bleeding occurs in up to 20%. At this moment no laboratory...
Main Authors: | Saartje Bloemen, Suzanne Zwaveling, Hugo Ten Cate, Arina Ten Cate-Hoek, Bas de Laat |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5417600?pdf=render |
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