Association of alpha globin gene copy number with exhaled nitric oxide in a cross-sectional study of healthy Black adults

Introduction The genetic determinants of fractional exhalation of nitric oxide (FeNO), a marker of lung inflammation, are understudied in Black individuals. Alpha globin (HBA) restricts nitric oxide signalling in arterial endothelial cells via interactions with nitric oxide synthase; however, its ro...

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Bibliographic Details
Main Authors: Michael P Fay, Loretta G Que, A Parker Ruhl, Jarrett M Jackson, Carlos J Carhuas, Jessica G Niño de Rivera, J Brice Weinberg, Hans C Ackerman
Format: Article
Language:English
Published: BMJ Publishing Group 2023-12-01
Series:BMJ Open Respiratory Research
Online Access:https://bmjopenrespres.bmj.com/content/10/1/e001714.full