Nicotinamide enhances myelin production after demyelination through reduction of astrogliosis and microgliosis

Caloric restriction is the chronic reduction of total caloric intake without malnutrition and has attracted a lot of attention as, among multiple other effects, it attenuates demyelination and stimulates remyelination. In this study we have evaluated the effect of nicotinamide (NAM), a well-known ca...

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Bibliographic Details
Main Authors: Stefanos Ioannis Kaplanis, Despoina Kaffe, Niki Ktena, Andriani Lygeraki, Ourania Kolliniati, Maria Savvaki, Domna Karagogeos
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2023.1201317/full