The effects of tramadol on norepinephrine and MHPG releasing in locus coeruleus in formalin test in rats: a brain stereotaxic study

Objective(s):The relationship between tramadol, as an antinociceptive drug, and locus coeruleus (LC), the main noradrenergic nucleus of the brain that affects regulation and modulation of pain through descending noradrenergic pathways was investigated. Materials and Methods: Male Sprague-Dawley rats...

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Bibliographic Details
Main Authors: Mohammad Ali Mobasher, Javad Sajedianfard, Akram Jamshidzadeh, Naser Naghdi, Mohammad Mehdi Namvaran
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2014-06-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:http://ijbms.mums.ac.ir/pdf_2926_9105b316871d19fcb527245b2cbc7093.html