Remibrutinib inhibits hives effector cells stimulated by serum from chronic urticaria patients independently of FcεR1 expression level and omalizumab clinical response

Remibrutinib inhibits hives effector cells stimulated by serum from chronic urticaria patients independently of FcεR1 expression level and omalizumab clinical response

Abstract Background Despite advances in the treatment of chronic urticaria, in a significant percentage of the patients symptoms are not fully controlled with conventional approaches. New strategies under development include blocking intracellular mediators of mast cell and basophil activation. Obje...

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Bibliographic Details
Main Authors: Ramón Gimeno, Clara Ribas‐Llauradó, David Pesque, Evelyn Andrades, Bruno Cenni, Barbara Ambros, Ramon Pujol, Ana M. Giménez‐Arnau
Format: Article
Language:English
Published: Wiley 2023-03-01
Series:Clinical and Translational Allergy
Subjects:
basophils
Bruton's tyrosine kinase
chronic urticaria
IgE
mast cells
omalizumab
Online Access:https://doi.org/10.1002/clt2.12227

Internet

https://doi.org/10.1002/clt2.12227

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