Two distinct etiologies of gastric cardia adenocarcinoma: interactions among pH, Helicobacter pylori, and bile acids

Gastric cancer can be classified as cardia and noncardia subtypes according to the anatomic site. Although the gastric cancer incidence has decreased steadily in several countries over the past 50 years, the incidence of cardia cancers and esophageal adenocarcinoma (EAC) continue to increase. The et...

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Bibliographic Details
Main Authors: Ken-ichi eMukaisho, Takahisa eNakayama, Tadashi eHagiwara, Takanori eHattori, Hiroyuki eSugihara
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00412/full