New Cytotoxic Cerebrosides from the Red Sea Cucumber <i>Holothuria spinifera</i> Supported by <i>In-Silico</i> Studies

New Cytotoxic Cerebrosides from the Red Sea Cucumber <i>Holothuria spinifera</i> Supported by <i>In-Silico</i> Studies

Bioactivity-guided fractionation of a methanolic extract of the Red Sea cucumber <i>Holothuria spinifera</i> and LC-HRESIMS-assisted dereplication resulted in the isolation of four compounds, three new cerebrosides, spiniferosides A (<b>1</b>), B (<b>2</b>), and C...

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Bibliographic Details
Main Authors: Reda F. A. Abdelhameed, Enas E. Eltamany, Dina M. Hal, Amany K. Ibrahim, Asmaa M. AboulMagd, Tarfah Al-Warhi, Khayrya A. Youssif, Adel M. Abd El-kader, Hashim A. Hassanean, Shaimaa Fayez, Gerhard Bringmann, Safwat A. Ahmed, Usama Ramadan Abdelmohsen
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Marine Drugs
Subjects:
LC-HRESIMS
<i>Holothuria spinifera</i>
cerebrosides
molecular docking
cytotoxicity
Online Access:https://www.mdpi.com/1660-3397/18/8/405

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https://www.mdpi.com/1660-3397/18/8/405

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