A Race-Specific, DNA Methylation Analysis of Aging in Normal Rectum: Implications for the Biology of Aging and Its Relationship to Rectal Cancer

A Race-Specific, DNA Methylation Analysis of Aging in Normal Rectum: Implications for the Biology of Aging and Its Relationship to Rectal Cancer

Approximately 90% of colorectal cancer (CRC) develop over the age of 50, highlighting the important role of aging in CRC risk. African Americans (AAs) shoulder a greater CRC burden than European Americans (EA) and are more likely to develop CRC at a younger age. The effects of aging in AA and EA nor...

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Bibliographic Details
Main Authors: Matthew A. Devall, Xiangqing Sun, Stephen Eaton, Gregory S. Cooper, Joseph E. Willis, Daniel J. Weisenberger, Graham Casey, Li Li
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cancers
Subjects:
rectum
colorectal cancer
DNA methylation
epigenetic aging
racial disparities
African American
Online Access:https://www.mdpi.com/2072-6694/15/1/45

Internet

https://www.mdpi.com/2072-6694/15/1/45

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