New anti-diabetic drug Morus alba L. (Sangzhi) alkaloids (SZ-A) improves diabetic nephropathy through ameliorating inflammation and fibrosis in diabetic rats

New anti-diabetic drug Morus alba L. (Sangzhi) alkaloids (SZ-A) improves diabetic nephropathy through ameliorating inflammation and fibrosis in diabetic rats

BackgroundMorus alba L. (Sangzhi) alkaloid (SZ-A) is a new antidiabetic drug approved by the China National Medical Products Administration in 2020. Diabetic nephropathy (DN) is a common diabetic complication and an important cause of morbidity and mortality in patients with diabetes. The effects of...

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Bibliographic Details
Main Authors: Caina Li, Quan Liu, Wenming Ji, Yaxin Fu, Hui Cao, Yi Huan, Lei Lei, Xuefeng Gao, Leilei Chen, Cunyu Feng, Lin Zhang, Pingping Li, Yuling Liu, Shuainan Liu, Zhufang Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Medicine
Subjects:
Morus alba L. (Sangzhi) alkaloids
diabetic nephropathy
oxidative stress
nitrosative stress
inflammation
renal fibrosis
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2023.1164242/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2023.1164242/full

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