Hepatoprotective activity of andrographolide possibly through antioxidative defense mechanism in Sprague-Dawley rats

Hepatoprotective activity of andrographolide possibly through antioxidative defense mechanism in Sprague-Dawley rats

The aims of this study to assess the efficiency of AGL against acetaminophen (APAP)-induced hepatic toxicity that was generated by mitochondrial oxidative stress and glutathione depletion. Free radical scavenging potentiality was analyzed by using 2, 2-diphenyl-1-picrylhydrazyl (DPPH), hydrogen pero...

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Bibliographic Details
Main Authors: Milon Mondal, Chandan Sarkar, Sushmita Saha, Md Naim Hossain, Roghayeh Norouzi, Mohammad S. Mubarak, Abolghasem Siyadatpanah, Polrat Wilairatana, Rajib Hossain, Muhammad Torequl Islam, Henrique Douglas Melo Coutinho
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Toxicology Reports
Subjects:
Andrographolide
Acetaminophen
Oxidative stress, Anti-oxidant, Hepatoprotective activity
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750022000919

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http://www.sciencedirect.com/science/article/pii/S2214750022000919

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