Using object oriented bayesian networks to model linkage, linkage disequilibrium and mutations between STR markers.

In a number of applications there is a need to determine the most likely pedigree for a group of persons based on genetic markers. Adequate models are needed to reach this goal. The markers used to perform the statistical calculations can be linked and there may also be linkage disequilibrium (LD) i...

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Bibliographic Details
Main Authors: Daniel Kling, Thore Egeland, Petter Mostad
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3439468?pdf=render