A Boronated Derivative of Temozolomide Showing Enhanced Efficacy in Boron Neutron Capture Therapy of Glioblastoma

There is an incontestable need for improved treatment modality for glioblastoma due to its extraordinary resistance to traditional chemoradiation therapy. Boron neutron capture therapy (BNCT) may play a role in the future. We designed and synthesized a <sup>10</sup>B-boronated derivative...

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Bibliographic Details
Main Authors: Jing Xiang, Lin Ma, Zheng Gu, Hongjun Jin, Hongbin Zhai, Jianfei Tong, Tianjiao Liang, Juan Li, Qiushi Ren, Qi Liu
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/11/7/1173