Identifying the genetic basis of viral spillover using Lassa virus as a test case

Identifying the genetic basis of viral spillover using Lassa virus as a test case

The rate at which zoonotic viruses spill over into the human population varies significantly over space and time. Remarkably, we do not yet know how much of this variation is attributable to genetic variation within viral populations. This gap in understanding arises because we lack methods of genet...

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Bibliographic Details
Main Authors: Alexander O. B. Whitlock, Brian H. Bird, Bruno Ghersi, Andrew J. Davison, Joseph Hughes, Jenna Nichols, Matej Vučak, Emmanuel Amara, James Bangura, Edwin G. Lavalie, Marilyn C. Kanu, Osman T. Kanu, Anna Sjodin, Christopher H. Remien, Scott L. Nuismer
Format: Article
Language:English
Published: The Royal Society 2023-03-01
Series:Royal Society Open Science
Subjects:
genome-wide association studies
Lassa virus
zoonosis
single-nucleotide polymorphisms
spillover
host shift
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsos.221503

Internet

https://royalsocietypublishing.org/doi/10.1098/rsos.221503

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