The intestinal permeability marker FITC-dextran 4kDa should be dosed according to lean body mass in obese mice
Abstract Aims To investigate the influence of the dose in the FITC-Dextran 4kDa (FD-4) permeability test in an obese mouse model, we tested the bodyweight dose regimen and a lean body mass-based dose regimen in high fat diet (HFD) mice and low fat diet (LFD) mice. We hypothesized that the FD-4 perme...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-01-01
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Series: | Nutrition & Diabetes |
Online Access: | https://doi.org/10.1038/s41387-022-00230-2 |