The intestinal permeability marker FITC-dextran 4kDa should be dosed according to lean body mass in obese mice

Abstract Aims To investigate the influence of the dose in the FITC-Dextran 4kDa (FD-4) permeability test in an obese mouse model, we tested the bodyweight dose regimen and a lean body mass-based dose regimen in high fat diet (HFD) mice and low fat diet (LFD) mice. We hypothesized that the FD-4 perme...

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Bibliographic Details
Main Authors: Louise M. Voetmann, Bidda Rolin, Rikke K. Kirk, Charles Pyke, Axel K. Hansen
Format: Article
Language:English
Published: Nature Publishing Group 2023-01-01
Series:Nutrition & Diabetes
Online Access:https://doi.org/10.1038/s41387-022-00230-2

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