FLT3 mutations in canine acute lymphocytic leukemia

<p>Abstract</p> <p>Background</p> <p>FMS-like tyrosine kinase 3 (FLT3) is a commonly mutated protein in a variety of human acute leukemias. Mutations leading to constitutively active FLT3, including internal tandem duplications of the juxtamembrane domain (ITD), result...

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Bibliographic Details
Main Authors: Seiser Eric L, Small George W, Suter Steven E, Thomas Rachael, Breen Matthew, Richards Kristy L
Format: Article
Language:English
Published: BMC 2011-01-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/11/38