Placental mTOR Signaling and Sexual Dimorphism in Metabolic Health across the Lifespan of Offspring

Robust evidence of fetal programming of adult disease has surfaced in the last several decades. Human and preclinical investigations of intrauterine insults report perturbations in placental nutrient sensing by the mechanistic target of rapamycin (mTOR). This review focuses on pregnancy complication...

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Bibliographic Details
Main Authors: Megan Beetch, Emilyn U. Alejandro
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Children
Subjects:
Online Access:https://www.mdpi.com/2227-9067/8/11/970