Gradual Versus Abrupt Reperfusion During Primary Percutaneous Coronary Interventions in ST‐Segment–Elevation Myocardial Infarction (GUARD)

Gradual Versus Abrupt Reperfusion During Primary Percutaneous Coronary Interventions in ST‐Segment–Elevation Myocardial Infarction (GUARD)

Background Intramyocardial edema and hemorrhage are key pathological mechanisms in the development of reperfusion‐related microvascular damage in ST‐segment–elevation myocardial infarction. These processes may be facilitated by abrupt restoration of intracoronary pressure and flow triggered by prima...

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Bibliographic Details
Main Authors: Murat Sezer, Javier Escaned, Christopher J. Broyd, Berrin Umman, Zehra Bugra, Ilke Ozcan, Mehmet Rasih Sonsoz, Alp Ozcan, Adem Atici, Emre Aslanger, Z. Irem Sezer, Justin E. Davies, Niels van Royen, Sabahattin Umman
Format: Article
Language:English
Published: Wiley 2022-05-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
coronary microvascular resistance
intramyocardial hemorrhage
microvascular injury
myocardial edema
primary PCI
reperfusion injury
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.121.024172

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https://www.ahajournals.org/doi/10.1161/JAHA.121.024172

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