Serum and Urinary Soluble α-Klotho as Markers of Kidney and Vascular Impairment

Serum and Urinary Soluble α-Klotho as Markers of Kidney and Vascular Impairment

This study was designed to investigate the controversy on the potential role of sKlotho as an early biomarker in Chronic Kidney Disease–Mineral Bone Disorder (CKD-MBD), to assess whether sKlotho is a reliable marker of kidney α-Klotho, to deepen the effects of sKlotho on vascular smooth muscle cells...

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Bibliographic Details
Main Authors: Julia Martín-Vírgala, Sara Fernández-Villabrille, Beatriz Martín-Carro, Isaac Tamargo-Gómez, Juan F. Navarro-González, Carmen Mora-Fernández, Laura Calleros, Elena Astudillo-Cortés, Noelia Avello-Llano, Guillermo Mariño, Adriana S. Dusso, Cristina Alonso-Montes, Sara Panizo, Jorge B. Cannata-Andía, Manuel Naves-Díaz, Natalia Carrillo-López
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Nutrients
Subjects:
sKlotho
chronic kidney disease
osteogenic differentiation
serum CKD-MBD biomarkers
vascular calcification
Online Access:https://www.mdpi.com/2072-6643/15/6/1470

Internet

https://www.mdpi.com/2072-6643/15/6/1470

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