Deacetylation of H4-K16Ac and heterochromatin assembly in senescence

<p>Abstract</p> <p>Background</p> <p>Cellular senescence is a stress response of mammalian cells leading to a durable arrest of cell proliferation that has been implicated in tumor suppression, wound healing, and aging. The proliferative arrest is mediated by transcript...

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Autori principali: Contrepois Kévin, Thuret Jean-Yves, Courbeyrette Régis, Fenaille François, Mann Carl
Natura: Articolo
Lingua:English
Pubblicazione: BMC 2012-08-01
Serie:Epigenetics & Chromatin
Accesso online:http://www.epigeneticsandchromatin.com/content/5/1/15