Crystal structure of the GDSL family esterase EstL5 in complex with PMSF reveals a branch channel of the active site pocket

Crystal structure of the GDSL family esterase EstL5 in complex with PMSF reveals a branch channel of the active site pocket

Esterases/lipases from the GDSL family have potential applications in the hydrolysis and synthesis of important esters of pharmaceutical, food, and biotechnical interests. However, the structural and functional understanding of GDSL enzymes is still limited. Here, we report the crystal structure of...

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Bibliographic Details
Main Authors: Chen Runsha, Gao Xuechun, Nie Ting, Wu Jinhong, Wang Lin, Osman Ali, Feng Yan, Li Xianghong, Zhang Yong
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2023-09-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
GSDL esterase
PMSF
cavity
channel
crystal structure
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2023108

Internet

https://www.sciengine.com/doi/10.3724/abbs.2023108

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