Investigating the molecular genetic, genomic, brain structural, and brain functional correlates of latent transdiagnostic dimensions of psychopathology across the lifespan: Protocol for a systematic review and meta-analysis of cross-sectional and longitudinal studies in the general population

BackgroundResearch using latent variable modelling has identified a superordinate general dimension of psychopathology, as well as several specific/lower-order transdiagnostic dimensions (e.g., internalising and externalising) within the meta-structure of psychiatric symptoms. These models can facil...

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Bibliographic Details
Main Authors: Nicholas Hoy, Samantha Lynch, Monika Waszczuk, Simone Reppermund, Louise Mewton
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Psychiatry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2022.1036794/full