A novel co-culture model for investigation of the effects of LPS-induced macrophage-derived cytokines on brain endothelial cells.

In order to study effects of macrophage-derived inflammatory mediators associated with systemic inflammation on brain endothelial cells, we have established a co-culture system consisting of bEnd.3 cells and LPS-activated Raw 264.7 cells and performed its cytokine profiling. The cytokine profile of...

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Bibliographic Details
Main Authors: Junling Yang, Yinchuan Li, Ambuj Bhalla, Mark Maienschein-Cline, Ken-Ichiro Fukuchi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0288497&type=printable