ICAM-1 Targeted Drug Combination Nanoparticles Enhanced Gemcitabine-Paclitaxel Exposure and Breast Cancer Suppression in Mouse Models

ICAM-1 Targeted Drug Combination Nanoparticles Enhanced Gemcitabine-Paclitaxel Exposure and Breast Cancer Suppression in Mouse Models

Despite the availability of molecularly targeted treatments such as antibodies and small molecules for human epidermal growth factor receptor 2 (HER2), hormone receptor (HR), and programmed death-ligand 1 (PD-L1), limited treatment options are available for advanced metastatic breast cancer (MBC), w...

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Bibliographic Details
Main Authors: Linxi Zhu, Qingxin Mu, Jesse Yu, James I. Griffin, Xiaolin Xu, Rodney J. Y. Ho
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Pharmaceutics
Subjects:
metastatic breast cancer
nanoparticles
ICAM-1
targeting
combination therapy
Online Access:https://www.mdpi.com/1999-4923/14/1/89

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https://www.mdpi.com/1999-4923/14/1/89

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