Exploring the mTOR Signalling Pathway and Its Inhibitory Scope in Cancer

Exploring the mTOR Signalling Pathway and Its Inhibitory Scope in Cancer

Mechanistic target of rapamycin (mTOR) is a protein kinase that regulates cellular growth, development, survival, and metabolism through integration of diverse extracellular and intracellular stimuli. Additionally, mTOR is involved in interplay of signalling pathways that regulate apoptosis and auto...

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Bibliographic Details
Main Authors: Suhail Ahmad Mir, Ashraf Dar, Saad Ali Alshehri, Shadma Wahab, Laraibah Hamid, Mohammad Ali Abdullah Almoyad, Tabasum Ali, Ghulam Nabi Bader
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Pharmaceuticals
Subjects:
cancer
regulation of mTOR signalling pathway
mTORC1/2
mTOR inhibitors
rapamycin
Online Access:https://www.mdpi.com/1424-8247/16/7/1004

Internet

https://www.mdpi.com/1424-8247/16/7/1004

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