The Interplay between Colon Cancer Cells and Tumour-Associated Stromal Cells Impacts the Biological Clock and Enhances Malignant Phenotypes

Cancer cells interrelate with the bordering host microenvironment that encompasses the extracellular matrix and a nontumour cellular component comprising fibroblasts and immune-competent cells. The tumour microenvironment modulates cancer onset and progression, but the molecular factors managing thi...

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Bibliographic Details
Main Authors: Luise Fuhr, Mónica Abreu, Annalucia Carbone, Rukeia El-Athman, Fabrizio Bianchi, Mikko O. Laukkanen, Gianluigi Mazzoccoli, Angela Relógio
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/11/7/988