NF-κB modifies the mammalian circadian clock through interaction with the core clock protein BMAL1.

NF-κB modifies the mammalian circadian clock through interaction with the core clock protein BMAL1.

In mammals, the circadian clock coordinates cell physiological processes including inflammation. Recent studies suggested a crosstalk between these two pathways. However, the mechanism of how inflammation affects the clock is not well understood. Here, we investigated the role of the proinflammatory...

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Bibliographic Details
Main Authors: Yang Shen, Mehari Endale, Wei Wang, Andrew R Morris, Lauren J Francey, Rachel L Harold, David W Hammers, Zhiguang Huo, Carrie L Partch, John B Hogenesch, Zhao-Hui Wu, Andrew C Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-11-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1009933

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https://doi.org/10.1371/journal.pgen.1009933

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