Snail2 induced E-cadherin suppression and metastasis in lung carcinoma facilitated by G9a and HDACs

Snail2 is a repressor of E-cadherin during carcinogenesis; however, the specific mechanisms involved in this process remain largely unknown. Here, we determined that Snail2 was highly increased during TGF-β-induced EMT process in lung cells. H3K9 methylation was up-regulated and H3K4/H3K56 acetylati...

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Bibliographic Details
Main Authors: Yue Hu, Yayuan Zheng, Mingrui Dai, Jiaxin Wu, Bin Yu, Haihong Zhang, Wei Kong, Hui Wu, Xianghui Yu
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Cell Adhesion & Migration
Subjects:
Online Access:http://dx.doi.org/10.1080/19336918.2019.1638689