Poly(A) binding protein 1 enhances cap-independent translation initiation of neurovirulence factor from avian herpesvirus.

Poly(A) binding protein 1 enhances cap-independent translation initiation of neurovirulence factor from avian herpesvirus.

Poly(A) binding protein 1 (PABP1) plays a central role in mRNA translation and stability and is a target by many viruses in diverse manners. We report a novel viral translational control strategy involving the recruitment of PABP1 to the 5' leader internal ribosome entry site (5L IRES) of an im...

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Bibliographic Details
Main Authors: Abdessamad Tahiri-Alaoui, Yuguang Zhao, Yashar Sadigh, James Popplestone, Lydia Kgosana, Lorraine P Smith, Venugopal Nair
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4263670?pdf=render

Internet

http://europepmc.org/articles/PMC4263670?pdf=render

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