Hypoxia‐inducible factor‐1α contributes to the proliferation of cholesteatoma keratinocytes through regulating endothelin converting enzyme 1 expression
Abstract Objective Cholesteatoma is a hyperproliferative, pseudoneoplastic lesion of the middle ear characterized by aggressive growth and bone destruction. Hypoxia‐inducible factor‐1α (HIF‐1α, also known as HIF1A) is a key transcription factor that enters the nucleus and upregulates many genes invo...
| Principais autores: | , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
Wiley
2024-04-01
|
| coleção: | Laryngoscope Investigative Otolaryngology |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1002/lio2.1233 |