Myosin Transducer Inter-Strand Communication Is Critical for Normal ATPase Activity and Myofibril Structure
The R249Q mutation in human β-cardiac myosin results in hypertrophic cardiomyopathy. We previously showed that inserting this mutation into <i>Drosophila melanogaster</i> indirect flight muscle myosin yields mechanical and locomotory defects. Here, we use transgenic <i>Drosophila&l...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-07-01
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| Series: | Biology |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-7737/11/8/1137 |