Olfactory receptors impact pathophysiological processes of lung diseases in bronchial epithelial cells

Olfactory receptors impact pathophysiological processes of lung diseases in bronchial epithelial cells

Background: Therapeutic options for steroid-resistant non-type 2 inflammation in obstructive lung diseases are limited. Bronchial epithelial cells are key in the pathogenesis by releasing the central proinflammatory cytokine interleukine-8 (IL-8). Olfactory receptors (ORs) are expressed in various c...

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Bibliographic Details
Main Authors: Daniel Weidinger, Julian Jacobsen, Desiree Alisch, Hendrik Uebner, Natalie Heinen, Lea Greune, Saskia Westhoven, Kaschin Jamal Jameel, Juliane Kronsbein, Stephanie Pfaender, Christian Taube, Sebastian Reuter, Marcus Peters, Hanns Hatt, Jürgen Knobloch
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:European Journal of Cell Biology
Subjects:
olfactory receptors
drug target
bronchial epithelium
non-type 2 inflammation, lung diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S0171933524000256

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http://www.sciencedirect.com/science/article/pii/S0171933524000256

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