PredPRBA: Prediction of Protein-RNA Binding Affinity Using Gradient Boosted Regression Trees

PredPRBA: Prediction of Protein-RNA Binding Affinity Using Gradient Boosted Regression Trees

Protein-RNA interactions play essential roles in many biological aspects. Quantifying the binding affinity of protein-RNA complexes is helpful to the understanding of protein-RNA recognition mechanisms and identification of strong binding partners. Due to experimentally measured protein-RNA binding...

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Bibliographic Details
Main Authors: Lei Deng, Wenyi Yang, Hui Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Genetics
Subjects:
protein-RNA interactions
computational approaches
binding affinity
gradient boosted regression tree
sequence and structural features
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00637/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2019.00637/full

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