Single-cell analysis reveals alterations in cellular composition and cell-cell communication associated with airway inflammation and remodeling in asthma

Single-cell analysis reveals alterations in cellular composition and cell-cell communication associated with airway inflammation and remodeling in asthma

Abstract Background Asthma is a heterogeneous disease characterized by airway inflammation and remodeling, whose pathogenetic complexity was associated with abnormal responses of various cell types in the lung. The specific interactions between immune and stromal cells, crucial for asthma pathogenes...

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Bibliographic Details
Main Authors: Xiu Yu, Lifei Li, Bicheng Cai, Wei Zhang, Quan Liu, Nan Li, Xing Shi, Li Yu, Rongchang Chen, Chen Qiu
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Respiratory Research
Subjects:
Asthma
Single-cell RNA-sequencing
Cell-cell communication
Airway inflammation
Airway remodeling
Online Access:https://doi.org/10.1186/s12931-024-02706-4

Internet

https://doi.org/10.1186/s12931-024-02706-4

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