Exosome-mediated miR-144-3p promotes ferroptosis to inhibit osteosarcoma proliferation, migration, and invasion through regulating ZEB1

Exosome-mediated miR-144-3p promotes ferroptosis to inhibit osteosarcoma proliferation, migration, and invasion through regulating ZEB1

Abstract Background Osteosarcoma (OS) is the most prevalent orthopedic malignancy with a dismal prognosis. The high iron absorption rate in OS cells of patients suggests that ferroptosis may be related to the progression of OS, but its potential molecular regulatory role is still unclear. Based on t...

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Bibliographic Details
Main Authors: Mingyang Jiang, Yiji Jike, Kaicheng Liu, Fu Gan, Ke Zhang, Mingjing Xie, Junlei Zhang, Chuanliang Chen, Xiaochong Zou, Xiaohong Jiang, Yongheng Dai, Weikui Chen, Yue Qiu, Zhandong Bo
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Molecular Cancer
Subjects:
Osteosarcoma
Exosome
miR-144-3p
ZEB1
Ferroptosis
Online Access:https://doi.org/10.1186/s12943-023-01804-z

Internet

https://doi.org/10.1186/s12943-023-01804-z

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