Differentiation of zebrafish melanophores depends on transcription factors AP2 alpha and AP2 epsilon.
A model of the gene-regulatory-network (GRN), governing growth, survival, and differentiation of melanocytes, has emerged from studies of mouse coat color mutants and melanoma cell lines. In this model, Transcription Factor Activator Protein 2 alpha (TFAP2A) contributes to melanocyte development by...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-09-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC2940735?pdf=render |