Medicinal fungus Phellinus igniarius alleviates gout in vitro by modulating TLR4/NF-kB/NLRP3 signaling

Medicinal fungus Phellinus igniarius alleviates gout in vitro by modulating TLR4/NF-kB/NLRP3 signaling

Background:Phellinus igniarius (P. igniarius) is a valuable medicinal and edible fungus with various biological activities such as anti-inflammation, antioxidation, and immune regulation. In this study, we explored the effects of P. igniarius on a gout model in vitro.Methods: The DPPH, ABTS, and FRA...

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Bibliographic Details
Main Authors: Xuebin Zhou, Qiyuan Shi, Jinhua Li, Shengli Quan, Xinyue Zhang, Lili Gu, Hongxing Li, Yue Ju, Min Hu, Qin Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Pharmacology
Subjects:
medicinal fungus Phellinus igniarius
anti-gout
metabolic mechanism
TLR4
NF-kB
NLRP3 inflammasome
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1011406/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.1011406/full

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