Crim1 and Kelch-like 14 exert complementary dual-directional developmental control over segmentally specific corticospinal axon projection targeting

Crim1 and Kelch-like 14 exert complementary dual-directional developmental control over segmentally specific corticospinal axon projection targeting

Summary: The cerebral cortex executes highly skilled movement, necessitating that it connects accurately with specific brainstem and spinal motor circuitry. Corticospinal neurons (CSN) must correctly target specific spinal segments, but the basis for this targeting remains unknown. In the accompanyi...

Full description

Bibliographic Details
Main Authors: Vibhu Sahni, Yasuhiro Itoh, Sara J. Shnider, Jeffrey D. Macklis
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Cell Reports
Subjects:
corticospinal tract
cortical development
corticospinal circuitry
molecular controls over neuronal diversity
motor control
bulbar-cervical
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721013061

Internet

http://www.sciencedirect.com/science/article/pii/S2211124721013061

Similar Items