Analgesic effects of a highly selective mPGES-1 inhibitor

Abstract The growing opioid use and overdose crisis in the US is closely related to the abuse of pain medications. Particularly for postoperative pain (POP), ~ 310 million major surgeries are performed globally per year. Most patients undergoing surgical procedures experience acute POP, and ~ 75% of...

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Bibliographic Details
Main Authors: Madeline J. Stewart, Lauren M. Weaver, Kai Ding, Annet Kyomuhangi, Charles D. Loftin, Fang Zheng, Chang-Guo Zhan
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-30164-3