Jatrorrhizine inhibits Piezo1 activation and reduces vascular inflammation in endothelial cells

Jatrorrhizine inhibits Piezo1 activation and reduces vascular inflammation in endothelial cells

Vascular inflammation is a common pathological basis underlying many cardiovascular diseases. As such, the treatment of vascular inflammation has attracted increasing attention. The Piezo1 pathway has long been shown to play an important role in the development of vascular inflammation. Jatrorrhizin...

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Bibliographic Details
Main Authors: Tianying Hong, Xianmei Pan, Han Xu, Zhijuan Zheng, Lizhen Wen, Jing Li, Mingfeng Xia
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Vascular inflammation
Endothelial injury
Piezo1
Jatrorrhizine
Endothelial-to-mesenchymal transition
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223005449

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http://www.sciencedirect.com/science/article/pii/S0753332223005449

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