Protective effects of intracerebroventricular adiponectin against olfactory impairments in an amyloid β1–42 rat model

Protective effects of intracerebroventricular adiponectin against olfactory impairments in an amyloid β1–42 rat model

Abstract Background Alzheimer’s disease (AD) is characterized by cognitive impairment that eventually develops into dementia. Amyloid-beta (Aβ) accumulation is a widely described hallmark in AD, and has been reported to cause olfactory dysfunction, a condition considered an early marker of the disea...

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Main Authors: Mara A. Guzmán-Ruiz, Amor Herrera-González, Adriana Jiménez, Alan Candelas-Juárez, Crystal Quiroga-Lozano, Claudia Castillo-Díaz, Erika Orta-Salazar, Diana Organista-Juárez, Sofía Díaz-Cintra, Rosalinda Guevara-Guzmán
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Neuroscience
Subjects:
Adiponectin
Amyloid-beta
Alzheimer disease model
Hippocampus
Olfactory bulb
Olfactory dysfunction
Online Access:https://doi.org/10.1186/s12868-021-00620-9

Internet

https://doi.org/10.1186/s12868-021-00620-9

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