Synthetic (<i>E</i>)-3-Phenyl-5-(phenylamino)-2-styryl-1,3,4-thiadiazol-3-ium Chloride Derivatives as Promising Chemotherapy Agents on Cell Lines Infected with HTLV-1

Synthetic (<i>E</i>)-3-Phenyl-5-(phenylamino)-2-styryl-1,3,4-thiadiazol-3-ium Chloride Derivatives as Promising Chemotherapy Agents on Cell Lines Infected with HTLV-1

Synthesis of four compounds belonging to mesoionic class, (<i>E</i>)-3-phenyl-5-(phenylamino)-2-styryl-1,3,4-thiadiazol-3-ium chloride derivatives (<b>5a</b>–<b>d</b>) and their biological evaluation against MT2 and C92 cell lines infected with human T-cell lympho...

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Bibliographic Details
Main Authors: Danilo Sousa-Pereira, Thais Silva de Oliveira, Rojane O. Paiva, Otávio Augusto Chaves, José C. Netto-Ferreira, Juliana Echevarria-Lima, Aurea Echevarria
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Molecules
Subjects:
mesoionic compounds
HTLV-1
HSA interaction
multiple spectroscopic
molecular docking
Online Access:https://www.mdpi.com/1420-3049/25/11/2537

Internet

https://www.mdpi.com/1420-3049/25/11/2537

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