Increase in CD4+Foxp3+ Regulatory T cells and Amelioration of Experimental Autoimmune Encephalomyelitis in Mice Treated with IL-27

Increase in CD4+Foxp3+ Regulatory T cells and Amelioration of Experimental Autoimmune Encephalomyelitis in Mice Treated with IL-27

Background and purpose: In multiple sclerosis (MS) and its murine model, experimental autoimmune encephalomyelitis (EAE), chronic inflammation damages the myelin of central nervous system. Recently, interleukin-27 (IL-27) has been recognized as a feasible choice for treatment of autoimmune diseases...

Full description

Bibliographic Details
Main Authors: Samad Nazemi, Rahim Golmohammadi, Mohsen Naeemipour, Mohammad-Shafi Mojadadi
Format: Article
Language:English
Published: Mazandaran University of Medical Sciences 2019-12-01
Series:Journal of Mazandaran University of Medical Sciences
Subjects:
il-27
experimental autoimmune encephalomyelitis
multiple sclerosis
il-17
ifn-γ
il-6
il-10
regulatory t cells
Online Access:http://jmums.mazums.ac.ir/article-1-12819-en.html

Internet

http://jmums.mazums.ac.ir/article-1-12819-en.html

Similar Items