Incarvillea compacta Maxim ameliorates inflammatory response via inhibiting PI3K/AKT pathway and NLRP3 activation

Incarvillea compacta Maxim ameliorates inflammatory response via inhibiting PI3K/AKT pathway and NLRP3 activation

Incarvillea compacta Maxim is a traditional Tibetan medicine used to treat inflammation-related diseases, such as pneumonia, fever, jaundice, and otitis media. However, no studies have examined its anti-inflammatory mechanism. To validate the anti-inflammatory activity of I. compacta extract (ICE) a...

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Bibliographic Details
Main Authors: Ji Zhang, Yujing Feng, Shengqiang Han, Xueting Guan, Ziliang He, Chao Song, Lingyun Lv, Qiaoyu Luo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Pharmacology
Subjects:
Incarvillea compacta Maxim
anti-inflammatory
RNA sequencing
PI3K/Akt signaling pathway
acute gastritis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1058012/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.1058012/full

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